开源研究
AI蛋白质设计
分子生物物理
A general Temperature-Guided Language model to design proteins of enhanced Stability and Activity
Fan Jiang, Mingchen Li, Jiajun Dong, Yuanxi Yu, Xinyu Sun, Banghao Wu, Jin Huang, Liqi Kang, etc, Liang Hong, Pan Tan.
Science Advances, 2024. 获取代码 (Github)
Enhancing efficiency of protein language models with minimal wet-lab data through few-shot learning
Ziyi Zhou, Liang Zhang, Yuanxi Yu, Banghao Wu, Mingchen Li, Liang Hong, Pan Tan.
Nature Communications, 2024. 获取代码 (Github)
ProSST: Protein Language Modeling with Quantized Structure and Disentangled Attention
Mingchen Li, Yang Tan, Xinzhu Ma, Bozitao Zhong, Huiqun Yu, Ziyi Zhou, Wanli Ouyang, Bingxin Zhou, Liang Hong, Pan Tan.
NeurIPS, 2024. 获取代码 (Github)
Semantical and Geometrical Protein Encoding Toward Enhanced Bioactivity and Thermostabilitye
Yang Tan, Bingxin Zhou, Lirong Zheng, Guisheng Fan, Liang Hong.
eLife, 2024. 获取代码 (Github)
Simple, Efficient and Scalable Structure-aware Adapter Boosts Protein Language Models
Yang Tan, Mingchen Li, Bingxin Zhou, Bozitao Zhong, Lirong Zheng, Pan Tan, Ziyi Zhou, Huiqun Yu, Guisheng Fan, Liang Hong.
JCIM, 2024. 获取代码 (Github)
Protein Representation Learning with Sequence Information Embedding: Does it Always Lead to a Better Performance?
Yang Tan, Lirong Zheng, Bozitao Zhong, Liang Hong, Bingxin Zhou.
IEEE BIBM, 2024. 获取代码 (Github)
Protsolm: Protein solubility prediction with multi-modal features
Yang Tan, Jia Zheng, Liang Hong, Bingxin Zhou.
IEEE BIBM, 2024. 获取代码 (Github)
PETA: evaluating the impact of protein transfer learning with sub-word tokenization on downstream applications
Yang Tan, Mingchen Li, Ziyi Zhou, Pan Tan, Huiqun Yu, Guisheng Fan, Liang Hong.
J. of Cheminformatics, 2024. 获取代码 (Github)